Position: Senior Scientist - Virology - Global Biotechnology Organisation
Title:

Senior Scientist, Viral Vector Research Duration:
Full-time, permanent

Location:

Based in Oxford Salary:
Great salary and bonus available Briefing notes We are searching for a Molecular Biologist/Virologist to join a team focused on therapeutic vaccines research and development.

Must have a minimum of a MSc Degree

Must have 2-4 years of hands on experience in gene editing/genetically modifying viruses in a academic/commercial laboratory setting Designing experiments and conducting research using a variety of methodologies; e.g. design and cloning of mammalian expression cassettes, PCR, DNA sequence interpretation, ELISA, western blot, viral growth curves, viral titers, transfections, virus purification Job Description We are looking for a Research Scientist with experience in viruses such as (but not limited to) adenovirus, adeno-associated virus, lentivirus, herpes virus, with a strong molecular... biology background as well as cell/virus culture experience.

The successful candidate will participate in the development of new approaches to generate immunotherapeutics against infectious diseases and cancer. The Research Scientist will play an integral role in designing, interpreting and conducting laboratory studies in the context of discovery and preclinical research phases of novel therapeutic products. Give input to the strategy and develop and conduct laboratory work involved in the design, construction, growth, and evaluation of viral vector vaccine candidates Keep up to date on the field of immunotherapeutics, and review and suggest new approaches, alternative laboratory methods, or new studies to improve the outcome of a given objective Perform quality control assays on research-grade viral vectored vaccine preparations (physical titer, infectious titer, sequence verification, transgene expression) Maintain and evaluate both mammalian and bacterial cell cultures for growth conditions, DNA purification and viral vector production, and interpret and present the data in a concise and orderly fashion.

Assist in studies to optimise the ability to manufacture viral-vectored vaccines, such as evaluation of alternative transfection systems, host or vector gene deletions or insertions, viral culture yield, systems for viral growth, etc. Evaluate and perform analytic assays to determine the quality, yield, stability, etc. of specific candidates or of specific manufacturing process conditions as required

Qualifications and experience required Master’s degree plus 4 years of laboratory experience, or a recent PhD, in virology/molecular biology Relevant work experience, with demonstrated experience in laboratory bench work with molecular biology and cell and virus culture systems Proficiency in designing experiments and conducting research using a variety of methodologies; e.g. design and cloning of mammalian expression cassettes, PCR, DNA sequence interpretation, ELISA, western blot, viral growth curves, viral titers, transfections, virus purification Excellent writing and communication skills;

ability to understand and communicate scientific information; proficiency in Powerpoint, graphic displays and tables A self-starter with the ability to work in a fast-paced environment and adapt quickly to changing needs and priorities; proven ability to priorities and manage multiple tasks simultaneously. If you would like to discuss this vacancy further or to discuss your career options in confidence, please telephone on +44 (0) or email me on:

If this role isn’t suitable for you, please let us know if you can refer anyone – any recommendations are much appreciated! Planet Pharma offers a competitive referral scheme so you will be rewarded for your help! About Planet Pharma Planet Pharma is an American parented Employment Business/Agency that provides global staffing services with its head-quarters in Chicago and our EMEA regional office located in Central London.

We have invested significantly in creating a robust international platform that enables us to work compliantly in 30+ countries with a current network of 2500+ active contractors globally as well as a very strong permanent / direct hire recruitment offering. Our specialist knowledge and close relationships with our clients and the wider industry really makes us unique in our field.

Just recently we were recognized by FORBES as the 17th best professional staffing firm, and have won multiple awards from industry accredited bodies for our commitment to excellence and service delivery. We have extensive functional expertise including:
Regulatory Affairs, Pharmacovigilance, QA, QC, Submissions experts, Clinical development, Quality, Biostatistics, and Medical Affairs / Writing. We are an equal opportunities Recruitment Business and Agency. We welcome applications from all suitably qualified candidates regardless of their race, sex, disability, religion/belief, sexual orientation or age
Oxford UK

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