Job Type






(Senior) Research Associate, Cancer Immunology Cambridge


BioNTech Cambridge MA United States

2 weeks ago

(Senior) Research Associate, Cancer Immunology

Become a member of the BioNTech Family...

Based in Cambridge, MA and Gaithersburg, MD. We are committed to improving the health of people worldwide with our fundamental research and our work in the area of development of immunotherapies utilizing the full potential of the immune system to fight cancer, infectious diseases and other serious diseases. We believe in scientific rigor, innovation and passion as driving forces. BioNTech was founded by scientists and physicians to translate science into survival by combining fundamental research and operational excellence.

With decades of deep immunology expertise and experience in developing and optimizing mRNA as part of its broad suite of novel technologies, the company is working with the global community to defeat life-threatening and serious diseases such as cancer, COVID-19, malaria and tuberculosis. The first ever approved mRNA vaccine was created in the labs of BioNTech in Mainz, Germany. A fully integrated immunotherapy powerhouse. We remain focused on bringing our broad pipeline of next-generation immunotherapies and vaccines to people around the world to address cancer, infectious diseases, as well as a growing list of other medical conditions. To accomplish this, we continue to be deeply rooted in science and academic research while also having built a fully integrated, global immunotherapy company with cGMP and GMP manufacturing facilities anchored around deep expertise in immunology and complemented by an expanding set of capabilities.

We are seeking a highly motivated (Senior) Research Associate to join BioNTech’s Cancer Immunology team focused on novel T cell receptor (TCR) T cell therapies targeting solid tumors at our Cambridge, MA location. Specifically, this role will be responsible for evaluating combination therapies and T cell modifications to enhance our TCR T cell therapies. As part of a multi-disciplinary team, you will work closely with other Cell Therapy teams at our US and Germany BioNTech sites.


The areas of responsibilities will include but are not limited to
• Culturing of human T cells and cancer cell lines
• Engineering of T cells using viral and non-viral methods
• Performing functional and phenotypic characterization of engineered T cells by multicolor flow cytometry, MSD, and cytotoxicity assays
• Assisting with sample processing and analysis of samples derived from in vivo models to study combination therapies with our TCR T cell therapy
• Tracking and compiling results in an electronic notebook
• Interacting with internal collaborators and external CROs
• Presenting results to other scientific teams

• BS or MS in immunology or related discipline, and 0-3 years relevant work experience
• Hands-on experience with in vitro work and cell culture
• Proactive, self-motivated team player with strong interpersonal skills, appropriate sense of urgency and the ability to work independently as well as in a collaborative environment to meet project goals
• Excellent attention to detail
• Comfortable in a fast-paced environment and able embrace change, while working to produce key deliverables in accordance with project timelines
• Strong verbal and written communication skills and ability to communicate results to a diverse cross-functional audience
• Curious by nature, highly motivated to learn and advance your skills/knowledge

• Demonstrated experience with flow cytometry and other immune related assays
• Background knowledge on Tcell and cancer biology.

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
• Medical, Dental and Vision Insurance
• Life, AD&D, STD and LTD Insurance
• HSA & FSA Spending Accounts
• Health & Wellness, including free onsite gym access
• Adoption & Surrogacy Assistance
• Vacation and Unlimited Sick Time
• Holidays and Floating Holidays, including discretionary winter shutdown
• 401(K) Plan with Significant Company Match
• Tuition Reimbursement and Professional Development
• Commuting Assistance and subsidized parking
• Discounted Home and Auto Insurance
• Pet Insurance

Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.
• BioNTech does not differentiate on the basis of gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!

BioNTech - As unique as you
Cambridge MA USA

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