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  • 1 month ago

jobs description

Software for animal-to-human scaling of biotherapeutics
• *Project**:
Animal-to-human scaling of novel biotherapeutics is an important step in drug development. We want to develop a software that integrates existing data on preclinical and clinical pharmacokinetics of different biotherapeutic formats with mathematical models. The software should be able to visualize pharmacokinetic profiles across different species and provide model predictions in animal and in human.
• *Internship Goals**:

- Review literature on monoclonal antibody kinetics in preclinical species and in human.
- Digitize literature data and build a pharmacokinetics data base.
- Develop mathematical models.
- Develop an interface to query data and mathematical models for the prediction in humans.
• *Requirements**:

- Rigorous, excellent analytical skills, pro-active.
- Entrepreneurial spirit.
- Good at communication of scientific topics.
- Proficient in oral and written English.
- Good mathematical and statistical... skills.
- Expert in scientific programming using R and Shiny.
- User interface design.
• *Languages**:
English (Advanced)
• *Location**:
Basel. Remote work possible after evaluation of situation.
• *Company**:
LYO-X is a Swiss company located in Basel providing global consulting and Systems Pharmacology modelling services dedicated to the preclinical and clinical development of biologics and cell-based therapies.
• *Contact
Basel Switzerland


Apply - Systems Pharmacology Internship Animal-to-human Basel