• Genomic Variant Analyst Philadelphia
  • Penn Medicine in Philadelphia, PA, United States
  • jobs
  • 4 weeks ago

jobs description

Penn Medicine is dedicated to our tripartite mission of providing the highest level of care to patients, conducting innovative research, and educating future leaders in the field of medicine. Working for this leading academic medical center means collaboration with top clinical, technical and business professionals across all disciplines
Today at Penn Medicine, someone will make a breakthrough. Someone will heal a heart, deliver hopeful news, and give comfort and reassurance. Our employees shape our future each day. Are you living your life's work?


Full Time - Day Shift

The Genomic Variant Analyst will be proficient using a variety of computational databases such as COSMIC, OncoKB, the UCSC genome browser, et al to aid in the interpretation of genomic variants. The successful candidate will be familiar with concepts in molecular biology and genomics, meticulous with complex data review and documentation, possess strong critical thinking and organizational skills, and communicate effectively in a team-oriented environment. The Genomic Variant Analyst demonstrates a thorough knowledge of Genomics Laboratory and Variant Analyst operations, including theoretical aspects of technical procedures, as well as department policies and routines with minimal technical supervision.

Applies knowledge and skills to accurately follow all lab post-analytical procedures covering data analysis and preliminary review. Follows all lab pre-analytical, analytical and post-analytical procedures covering specimen, analytical test system and result reporting requirements. • Reviews NGS data and investigates and annotates new variants. Takes appropriate corrective action according to established procedures when data analysis deviates from acceptable level. Documents all corrective actions taken. Immediately notifies Manager or Director if unable to resolve test system problems. Ensures data is not reported until all corrective action has been taken and the pipeline is performing within specifications • Monitors, performs, and documents all Quality Control issues. Identifies issues/factors that adversely affect test performance. Provides analytical support to staff, physicians, and personnel to resolve any issues related to data analysis. • Takes appropriate corrective action according to established procedures, when test system performance deviates from acceptable level. Documents all corrective actions taken including calling technical support. Immediately notifies Supervisor and/or Director if unable to resolve test system issue. Ensures test results are not reported until all corrective action has been taken and test system is performing within specifications. • Participates in Proficiency Testing and ensures proficiency testing is performed in the same manner as patient specimens. Maintains compliance with Proficiency Testing policies. As directed by the Manager, maintains and updates laboratory policies, procedure manuals and specified documents required for review by regulatory agencies. Ensures that all employees are kept up to date with these changes. • Assists the manager in specified activities that ensure laboratory compliance with all accreditation agencies. Compliance with Competency accreditation guidelines is a staff responsibility that must be completed annually. May function as the General Supervisor for selected duties when required. • Demonstrates initiative in continually improving personal knowledge, skills, and work experience; and in improving departmental functioning. • Works well with Manager and those in authority; works at establishing a good rapport and cooperative working relationship with all members of the laboratory; maintains a positive rapport with medical staff and hospital personnel. Responsible for maintaining adequate staffing . • As directed by the Manager, coordinates the training of new employees, rotating Fellows/Residents to interpret clinical NGS data and manage sample triage. Investigates laboratory incident reports and documents the findings as per UPHS procedures. • Performs duties in accordance with Penn Medicine and entity values, policies, and procedures • Other duties as assigned to support the unit, department, entity, and health system organization.

Master's Degree Molecular biology, genetics, or related field and 1+ years Genomic variant analysis in a Diagnostic Laboratory OR other genomic data analysis experience, required. Possess the ability to perform tasks that require accurate and specific color distinction, required.

We believe that the best care for our patients starts with the best care for our employees. Our employee benefits programs help our employees get healthy and stay healthy. We offer a comprehensive compensation and benefits program that includes one of the finest prepaid tuition assistance programs in the region. Penn Medicine employees are actively engaged and committed to our mission. Together we will continue to make medical advances that help people live longer, healthier lives.

Live Your Life's Work

We are an Equal Opportunity and Affirmative Action employer. Candidates are considered for employment without regard to race, ethnicity, color, sex, sexual orientation, gender identity, religion, national origin, ancestry, age, disability, marital status, familial status, genetic information, domestic or sexual violence victim status, citizenship status, military status, status as a protected veteran or any other status protected by applicable law
Philadelphia PA USA


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