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CAS 1397-89-3 Amphotericin B Sells Well In India +8619930505014

Hebei Guanlang Biotechnolgy Co., Ltd - 10 days ago
Yuhua Road
Shijiazhuang AL
600 USD

Product Description: The effective components in amphotericin B liposome amphotericin B, the cholesterol content can enhance the stability of the drug, as much as possible to amphotericin B retain maximum content in the filter layer, the combination of lower and cholesterol in human body cell membrane and enhance the combination of ergosterol of fungal cells, so as to play the biggest sterilization ability of amphotericin B. The mechanism of action is similar to amphotericin B, both of which combine with sterols (mainly ergosterols) on the fungal cell membrane to increase membrane permeability and leak out important substances (such as potassium ions, nucleotides and amino acids) inside the cell, leading to the death of fungal cells. Amphotericin B liposomes are currently available in three main dosage forms :(1) Amphotericin B liposomes (liposomes interlaced with amphotericin B). (2) Amphotericin B liposomes (amphotericin B is wrapped in liposomes). (3) Amphotericin B gel Chemicalbook mass dispersion (made by mixing cholesterol sulfate with equal amount of amphotericin B). The presence of these lipids in reticuloendothelial tissues (e.g., liver, spleen, and lung tissues) in the body reduces the distribution of the drug in renal tissues, thereby reducing the nephrotoxicity of amphotericin B. In addition, the serum creatinine level was elevated, hypokalemia was rare, and the toxicity associated with intravenous drip was significantly lower than that of amphotericin B. Therefore, amphotericin B liposomes not only retain the high antibacterial activity of amphotericin B, but also reduce its toxicity. This product has a good antibacterial effect on Cryptococcus neoformans, Candida albicans, Candida tropicalis, yeast, Aspergillus, Coccidia, Histoplasma, Blastomyces dermatitis, Blastomyces brasiliensis, Sporotrichum and so on. However, it has no activity against bacteria, rickettsia and viruses. Part of Aspergillus is resistant to this drug; Skin and psoriasis bacteria are mostly drug resistant.

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CAS 1397-89-3 Amphotericin B sells well in India +8619930505014 Hebei Guanlang Biotechnolgy Co., Ltd Shijiazhuang
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